Searchable abstracts of presentations at key conferences in endocrinology

ea0056p364 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Influence of HLA pattern on the age at onset of type 1 diabetes mellitus

Fernandez Pedro Gonzalez , Rubio Elsa Fernandez , Etxebarria Ines Urrutia , Frutos Teba Gonzalez , Machado Natalia Maruri , Gonzalez Luis Castano , Saenz Sonia Gaztambide

Aim: To determine, in type 1 diabetes mellitus (T1DM) patients, if there is any relationship between the age at onset and the number of HLA risk alleles for T1DM (DRB1*03 and DRB1*04).Methods: Retrospective study. We selected patients with T1DM diagnosis (pancreatic autoimmunity and insulin-dependent diabetes) and age at onset >15 years, identifying 275 subjects (59.6% men and 40.4% women), with a median age at onset of 31 years (interquartile range ...